Computational biology projects built with AI
Onco Compass
Finds the actionable mutations in a lung cancer sample
What it does
A tumour sample can carry tens of thousands of variants, and finding the few that point to a treatment is slow, manual work spread across databases. Onco Compass runs the pipeline end to end: it annotates and filters a lung cancer VCF, calculates tumour mutational burden, and lists the variants that have a targeted therapy, with the evidence level for each.
How it works
- Uploads a raw or already-annotated VCF and runs the pipeline as a job
- Calculates tumour mutational burden and the count of filtered variants
- Reports actionable variants with therapies and AMP/ASCO/CAP evidence levels, such as KRAS G12C with sotorasib and adagrasib
Built with VCF · Variant annotation · Tumour mutational burden · AMP/ASCO/CAP levels · Web app
A learner prototype built on public data, shared with the team's permission as part of their portfolio. It is not a clinical tool.
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EvidOnco
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